The National Museum of Nature and Science will create the best use of the museum’s resources such as specimens (including digital information), human resources, and educational exhibits to develop and implement new initiatives appropriate to the times.

• Cooperation with Private companies
  The Museum collaborates with companies in a variety of ways, such as cooperating with their social contribution activities and supervising their books, utilizing various resources, including the specimens and materials in the Museum's collection and researchers with expertise
• Cooperation with the local community in Ueno
  The Museum works on integrating various sectors of society into each other. The Museum contributes to its local communities in Ueno by working on joint events including “Ueno Museum Weeks”, “Spring Festival in Tokyo” and “Ueno, a Global Capital of Culture” with regional organizations and cultural facilities.
• Cooperation with museums
  The Museum supports to foster and promote active utilization of the regional museum networks in the aim of enhancing science literacy among people in the community. Specifically, the Museum lends out touring exhibitions and holds joint collaborative projects that combine touring exhibitions and educational/training initiatives.
• Japanese Council of Science Museums
  The Museum plays a central role in Japanese museum community and is president of the Japanese Council of Science Museums, which consists of 200 plus members including science museums and related facilities throughout the country.The museum offers learning sessions and information services, and supports research at international advanced science museums for its members.

The Museum's activities are shared broadly with the public through various means. They are provided through the Museum website and social networking services as well. The Museum publishes the “kahaku event,” a brochure covering current and upcoming events at the Museum, as well as an e-mail magazine containing essays and latest updates from lab researchers. For the news media, the Museum sends out “Director General's Message” written by the Director General himself, and a “Days at KAHAKU” leaflet which introduces the daily activities taking place at the Museum. The publication of the Museum's magazine of nature and science, “milsil”, and the online “column by researchers” via the website serves to share a wide range of information, not limited to introducing the Museum's exhibitions, but providing results of the Museum's research projects as well.